益生菌 Probiotics
B 4 C 1 D 1 U 2
適應症與證據等級
陰道健康 (BV) Vaginal Health
B 🟡 B 初步證據 附警語發布 🚨 高市場風險
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抗生素相關腹瀉 Antibiotic Associated Diarrhea
B 🟡 B 初步證據 附警語發布 🚨 高市場風險
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便秘 Constipation
B 🟡 B 初步證據 附警語發布 🚨 高市場風險
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異位性皮膚炎 Atopic Dermatitis
B 🟡 B 初步證據 附警語發布 ⚠️ 中度市場風險
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潰瘍性結腸炎 Ulcerative Colitis
C 🟠 C 薄弱證據 附警語發布 🚨 高市場風險
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免疫功能 / 感冒(URI)預防 Immune Function
D 🔴 D 反證據 主流反證據 🚨 高市場風險
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腹瀉 Diarrhea
U ⚫ U 未驗證 證據不足 ⚠️ 中度市場風險
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腸躁症 Irritable Bowel Syndrome
U ⚫ U 未驗證 證據不足 🚨 高市場風險
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法規與權威立場 (L4)
L4a · US FDA
立場:cautious
FDA has not approved any probiotic product for use as a drug or biological product in infants of any age
來源 ↗ L4b · EU EFSA
立場:against
a cause and effect relationship had not been established between the consumption of a combination of bacterial strains and reduction of gastro-intestinal discomfort
來源 ↗ L4c · UK NHS
立場:cautious
There's some evidence that probiotics may be helpful in some cases, such as helping to ease some symptoms of irritable bowel syndrome (IBS). But there's little evidence to support many health claims made about them.
來源 ↗ L4e · WHO
立場:neutral
probiotic supplementation with the strains Bifidobacterium longum subsp. Infantis DSM33361 and Lactobacillus rhamnosus GG
來源 ↗ 市場與行銷 (L10)
L10a · TW Market Channels
300 億 CFU 的益生菌
L10b · TW Legal Identity (TFDA)
有助於促進腸內益菌增加
L10c · TW Community (PTT/Dcard/Mobile01)
醫生開抗生素時擔心會導致腹瀉,所以會開益生菌,但益生菌需要跟抗生素錯開吃。抗生素不只消滅體內壞菌,好菌也無法倖免於難,妙利散(Clostridium Butyricum Miyairi)是少數能夠扛住抗生素的益生菌。