Tirzepatide (Mounjaro / Zepbound / 穆桂諾) Tirzepatide
A 2 B 1 C 1
適應症與證據等級
法規與權威立場 (L4)
L4a · US FDA
立場:supportive
MOUNJARO is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. WARNING: RISK OF THYROID C-CELL TUMORS — Tirzepatide causes thyroid C-cell tumors in rats. It is unknown whether MOUNJARO causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide-induced rodent thyroid C-cell …
來源 ↗ L4b · EU EFSA
立場:supportive
Mounjaro received a marketing authorisation valid throughout the EU on 15 September 2022. The active substance in Mounjaro, tirzepatide, acts in the same way as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Mounjaro is a prescription-only medicine indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct…
來源 ↗ L4c · UK NHS
立場:supportive
Tirzepatide is recommended as an option for managing overweight and obesity, alongside a reduced-calorie diet and increased physical activity in adults, only if they have: an initial body mass index (BMI) of at least 35 kg/m2 and at least 1 weight-related comorbidity. If less than 5% of the initial weight has been lost after 6 months on the highest tolerated dose, decide whether to continue tre…
來源 ↗ L4d · TW TFDA / 衛福部
立場:supportive
猛健樂注射劑15毫克/0.5毫升 (MOUNJARO Injection 15mg/0.5mL);許可證字號:衛部藥輸字第028468號;限由醫師使用;適應症:(1) 作為飲食及運動療法之外的輔助治療,用於改善第二型糖尿病成人病人之血糖控制;(2) 作為飲食及運動療法之外的輔助治療,用於體重控制(肥胖或過重);申請商:台灣禮來股份有限公司;發證日期:112-07-19
來源 ↗ L4e · WHO
立場:supportive
Tirzepatide (GLP-1/GIP dual receptor agonist) used as glucose lowering therapy for adults with type 2 diabetes mellitus with established cardiovascular disease or chronic kidney disease and obesity. High prices of medicines like semaglutide and tirzepatide are limiting access to these medicines.
來源 ↗ 市場與行銷 (L10)
L10a · TW Market Channels
依據衛福部藥事法規定,Mounjaro 猛健樂為處方藥物,不得透過網路、電商平台或非合法通路自行購買。使用前應由專業醫師進行完整的身體評估、代謝狀況分析及健康風險判斷後,才可開立處方並合法使用。猛健樂於2025年6月30日由衛福部正式核准增列體重控制適應症,屬自費項目,健保不給付。
L10b · TW Legal Identity (TFDA)
猛健樂注射劑15毫克/0.5毫升 MOUNJARO Injection 15 mg/0.5 mL 衛部藥輸字第028468號 限由醫師使用
L10c · TW Community (PTT/Dcard/Mobile01)
去年體檢數字不是很滿意,GPT超標(6X),有脂肪肝現象...GPT從6X -> 4X (打猛建樂兩個月左右量的)。推文補充:我打一個月脂肪肝就沒了,肝指數從60幾跑到20幾,第三個月InBody內臟脂肪指數從8跑到4