螺內酯 / 安達通 Spironolactone
A 3 B 1
適應症與證據等級
法規與權威立場 (L4)
L4a · US FDA
立場:supportive
Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats. Spironolactone should be used only in those conditions described under INDICATIONS AND USAGE. Unnecessary use of this drug should be avoided. ALDACTONE is indicated for: Treatment of NYHA Class III-IV heart failure and reduced ejection fraction to increase survival, manage edema, and to reduce the need for hosp…
來源 ↗ L4b · EU EFSA
立場:supportive
Qaialdo received marketing authorization on 26 May 2023. It is authorized to manage refractory oedema associated with congestive heart failure; hepatic cirrhosis with ascites and oedema, malignant ascites, nephrotic syndrome, and for diagnosis and treatment of primary aldosteronism and essential hypertension. The medicine can only be obtained with a prescription, and children should only be tre…
來源 ↗ L4c · UK NHS
立場:supportive
It's used to treat: swelling, in the ankles, feet and other parts of the body, caused by fluid build-up (oedema), heart failure, high blood pressure (hypertension) if other medicines have not worked. It's only available with a prescription. Spironolactone is not usually recommended during pregnancy. This is because it can potentially affect a baby's development. [Serious side effects include] h…
來源 ↗ L4d · TW TFDA / 衛福部
立場:supportive
安達通錠25 毫克 Aldactone Tablets 25 mg 衛署藥輸字第022610號 本藥須由醫師處方使用。適應症:利尿、高血壓、原發性醛類脂醇過多症。孕婦用藥分級:D 級。高血鉀症徵象(有高達26%病人發生,即使與Thiazide 利尿劑合用亦如此)。
來源 ↗ L4e · WHO
立場:supportive
Spironolactone is an aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism. More specifically, its antimineralocorticoid activity is responsible for its therapeutic efficacy in the treatment of edema, high blood pressure, heart failure, hyperaldosteronism, and ascites due to cirrhosis. Additionally, spironolactone reduces the rate of testosterone pr…
來源 ↗ 市場與行銷 (L10)
L10a · TW Market Channels
安達通錠25 毫克 Aldactone Tablets 25 mg 衛署藥輸字第022610號 本藥須由醫師處方使用
L10b · TW Legal Identity (TFDA)
安達通錠25 毫克 Aldactone Tablets 25 mg 衛署藥輸字第022610號 本藥須由醫師處方使用
L10c · TW Community (PTT/Dcard/Mobile01)