比菲德氏菌 BB536 Bifidobacterium longum BB536

GRN No. 877 — Bifidobacterium longum BB536. Intended use: ingredient in term infant formula at a level of 1 x 10^8 CFU per gram of product. FDA closure date: December 26, 2019. FDA letter: 'FDA has no questions' regarding the safety of Bifidobacterium longum BB536 when used as described in the notice. (Earlier GRN 268 covered use in conventional foods/beverages.)

Scientific Opinion on the substantiation of health claims related to Bifidobacterium longum BB536 and improvement of bowel regularity (ID 3004), normal resistance to cedar pollen allergens (ID 3006), and decreasing potentially pathogenic gastro-intestinal microorganisms (ID 3005) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. Conclusion: Bifidobacterium longum BB536 does not improve…

There's some evidence that probiotics may be helpful in some cases, such as helping to ease some symptoms of irritable bowel syndrome (IBS). But there's little evidence to support many health claims made about them. Probiotics are generally classed as food rather than medicine, which means they don't go through the rigorous testing medicines do.

健康食品查驗登記審查採雙軌制，第一軌為「個案審查」，第二軌為「規格標準審查」，通過審查的產品會給予健康食品(小綠人)標章，第一軌的產品上標有「衛部健食字第A00000號」，第二軌的產品標有「衛部健食規字第000000號」。目前健康食品可以宣稱的保健功效項目共有13項，包括調節血脂、胃腸功能改善、護肝、免疫調節、骨質保健、不易形成體脂肪、抗疲勞、輔助調整過敏體質、調節血糖、延緩衰老、牙齒保健、促進鐵吸收、輔助調節血壓。

Probiotics are live microorganisms which, when administered in adequate amounts, confer a health benefit on the host. (FAO/WHO 2002, Guidelines for the Evaluation of Probiotics in Food)

在台灣，健康食品可宣稱的保健功效包括「免疫調節」和「胃腸功能改善」等13項，產品所准許宣稱之保健功效取決於個別產品所提出科學驗證之結果。通過審查的產品會獲得健康食品標章，第一軌的產品上標有「衛部健食字第A00000號」。

Bifidobacterium longum is listed in the 可供食品使用原料彙整一覽表 (Approved Food Ingredient List) under the category of lactic acid bacteria (乳酸菌), and is approved for use as a food ingredient or in food processing.

食用BB536的花粉症患者在眼睛方面的症狀，相較於普通優格有非常明顯的改善；在鼻發癢、鼻塞、流鼻涕、喉嚨症狀方面也有改善。