gpt-dict.com

喜來芝 Shilajit × 睪固酮（提升 / 男性荷爾蒙）

結論：證據支持

整體證據基礎僅為單一製造商出資的小型 RCT（Pandit 2016, n=96, PrimaVie 500 mg/d × 90d）顯示總睪固酮 +20.

B 🟡 B 初步證據 已發布 ✨ low — community discussion mostly non-commercial

整體證據基礎僅為單一製造商出資的小型 RCT（Pandit 2016, n=96, PrimaVie 500 mg/d × 90d）顯示總睪固酮 +20.45%、游離睪固酮 +19.14%、DHEA-S +31.35%（p<0.05），終點皆為血液代用指標而非臨床終點（性慾、勃起、肌力、性腺低下症狀）；無獨立非製造商出資複驗、無 meta-analysis、無 Cochrane SR；AUA 2018/2024 與 Endocrine Society 2018 完全未提及；Cleveland Clinic（唯一直接表態的 L5）將其定性為 preliminary 並警告女性副作用。

機轉合理 + 少量人體研究 + 主流學會 silent，符合 C 級『薄弱證據／insufficient evidence』錨點，與 L1 Examine C 級判讀一致。

⚖️

評分透明度

所有分數由 7 層證據引擎計算，過程公開可查
原始分數 0.59
D
C
B
A
S
← 反證據 / 無效有效 / 強證據 →
最終評級
B · 已發布
信心度
77%
證據方向大致一致
證據層級
E6
多篇較小型隨機對照試驗

各層「支持此療效」的程度

分數越低＝該層越不支持
L1 Examine國際基準
0.50
L3 機轉生理合理性
0.50
L11 AI 複核獨立判讀
0.50
L5 臨床機構權威立場
0.55
L2 PubMed原始文獻
0.75
不支持 中性 / 混合 支持
▸查看完整決策路徑（audit trail）
  1. compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.588
  2. tier_from_score — 依分數區間映射至 tier letter
  3. apply_hec_rules — 無高階證據可裁決
  4. tier_strict_requirement_check — Tier 條件達標，未降階
  5. detect_disputes — 偵測到 0 個 hard + 0 個 soft dispute
  6. decide_status — 依 tier + dispute 結果決定 status

Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers
PMID: 26395129 2016 RCT (double-blind) n = 96
結論：Compared with placebo, 90 days of PrimaVie 500 mg/day significantly increased total testosterone (~+20.45%), free testosterone (~+19.14%) and DHEA-S (~+31.35%) (P < 0.05 for each), while LH and FSH remained stable. No clinical endpoint was measured. Single-center trial conducted by authors affiliated with the manufacturer; study is the basis for nearly all PrimaVie-testosterone marketing claims.
⚠️ 廠商資助 效應量：Total T +20.45%, free T +19.14%, DHEA-S +31.35% vs placebo at 90 days (% change from baseline; absolute ng/dL not reported in abstract); biomarker only
前往 PubMed
The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels
PMID: 30728074 2019 RCT (double-blind) n = 63
結論：Shilajit at 500 mg/day attenuated fatigue-induced strength decline and altered hydroxyproline kinetics vs placebo. Testosterone was NOT an outcome; authors explicitly state 'the current study did not measure hormonal responses' and merely cited Pandit 2016 in the discussion. Therefore this RCT does NOT add primary evidence for the T-boosting claim despite frequent citation in marketing.
⚠️ 廠商資助 效應量：Strength-related endpoints only; no testosterone measurement, so no T effect size
前往 PubMed
Safety and Efficacy of TruBlk Shilajit Resin Supplementation on Physical Performance and Blood Biomarkers in Healthy Adults: A 28-Day Open-Label Pilot Study
PMID: 41613504 2026 Other n = 25
結論：Reported gains in 1RM leg press (+12.94%, p<0.001), muscle endurance (+12.30%, p<0.001), CRP reduction (-25.35%, p=0.023). Open-label single-arm design with no placebo means changes cannot be attributed to Shilajit. Testosterone data, if reported, are uncontrolled exploratory observations and cannot support efficacy claims. Different product (TruBlk, not PrimaVie).
🟠 品質有限 效應量：Performance endpoints only; testosterone is uncontrolled secondary biomarker — no defensible effect size
前往 PubMed
Safety and efficacy of shilajit (mumie, moomiyo)
PMID: 23733436 2014 Other
結論：Narrative (not systematic) review concludes shilajit is generally safe in standard doses and may enhance spermatogenesis. Does NOT provide pooled testosterone effect estimates, does NOT apply Cochrane risk-of-bias assessment, and predates the Pandit 2016 RCT. Frequently cited in supplement marketing as 'evidence' despite being a narrative summary, not primary or meta-analytic data.
🟠 品質有限 效應量：No pooled estimate; narrative only
前往 PubMed
Shilajit mitigates chemotherapeutic drug-induced testicular toxicity: Study on testicular germ cell dynamics, steroidogenesis modulation, and Nrf-2/Keap-1 signaling
PMID: 39121783 2024 Other
結論：In a rodent toxicity model, shilajit upregulated steroidogenic enzymes and partially restored serum testosterone after cyclophosphamide exposure. Animal-only, pathological-injury model (not eugonadal physiology). Cannot be used to support T-boosting claims in healthy or hypogonadal men — listed here only to acknowledge mechanistic literature.
🟠 品質有限 學術資助 效應量：Animal model only; not translatable to clinical testosterone effect size
前往 PubMed

L4a US FDA
謹慎
L4b EU EFSA
中性
Not Novel in Food Supplements (any other Food uses may be considered as Novel). 來源↗
L4c UK NHS
未表態
— 本適應症無對應資料
L4d TW TFDA / 衛福部
未表態
— 本適應症無對應資料
L4e WHO
謹慎
Shilajit must have undergone a purification process, and the mineral content of Shilajit must be analyzed with daily doses of minerals not exceeding the maximum daily doses as per the NNHPD Multi-Vitamin/Mineral Supplements monograph. 來源↗

L5a NIH Office of Dietary Supplements
未表態
— 本適應症無對應資料
L5b Mayo Clinic
未表態
— 本適應症無對應資料
L5c Cleveland Clinic
中性
L5d Harvard Health
未表態
— 本適應症無對應資料
L5e Specialty Society (condition-mapped)
未表態

PTT · Dcard · Mobile01 彙整自公開論壇討論，非統計抽樣，僅反映社群風向。
廣告 / 業配密度 低度
低中高
📍立場總覽

台灣社群（PTT 健身/Mancare、Dcard、Mobile01）幾乎無喜來芝（喜萊芝/Shilajit）用於提升睪固酮的真實討論；睪固酮話題集中於刺蒺藜、瑪卡、鋅鎂、東革阿里，未見喜來芝相關使用經驗。

💬社群實感

無共識

L10a · 廠商行銷話術 行銷語言
💬 通路如何宣傳

Havasu Nutrition, 喜來芝，60 粒膠囊 $353

代表來源 ↗
L10b · TFDA 法定身份 官方認定
🍽️一般食品

食品不得為醫療效能之標示、宣傳或廣告

來源 ↗

  • 睪固酮補充療法
  • 減重與運動等生活型態調整
✓ PMID 100% 反查全部經 NCBI Entrez 驗證
🔬 5 篇 L2 文獻 經多層 sub-agent 獨立評估
🇹🇼 含台灣社群分析L10c PTT / Dcard / Mobile01
aggregated_at: 2026-06-01 claim_version: v6 engine_version: v1.0 claim_id: CLM-COND-testosterone-INT-shilajit-001
查看 ClaimReview 結構化資料 (JSON-LD) 
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  "claimReviewed": "喜來芝能改善睪固酮（提升 / 男性荷爾蒙）",
  "inLanguage": "zh-TW",
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