印度人參 Ashwagandha × 壓力
結論:證據支持
客觀皮質醇下降證據強:2 篇 2025 高品質 MA (PMID 40746175 n=488; PMID 41140145 n=713) 與 L1 Examine Grade A (Cortisol, 3 studies n=254) 一致顯示顯著降低;壓力症狀 SMD -0.
B 🟡 B 初步證據 已發布 🚨 high — heavy affiliate marketing in TW community
客觀皮質醇下降證據強:2 篇 2025 高品質 MA (PMID 40746175 n=488; PMID 41140145 n=713) 與 L1 Examine Grade A (Cortisol, 3 studies n=254) 一致顯示顯著降低;壓力症狀 SMD -0.95 也有顯著改善。
但 PSS 主觀量表在最新 MA 顯示無顯著變化(客觀-主觀脫節),且無主流學會 (APA) first-line 推薦、L5d Harvard 未表態,故無法升至 S。
⚖️
評分透明度
所有分數由 7 層證據引擎計算,過程公開可查原始分數 0.62
D
C
B
A
S
← 反證據 / 無效有效 / 強證據 →
最終評級
B · 已發布
信心度
89%
證據方向一致性高
證據層級
E2
多篇高品質統合分析(≥2 篇一致)
▸查看完整決策路徑(audit trail)
- compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.621
- tier_from_score — 依分數區間映射至 tier letter
- apply_hec_rules — 高品質 SR/MA 顯示 positive (3 篇 > 0 negative)
- tier_strict_requirement_check — Tier 條件達標,未降階
- detect_disputes — 偵測到 0 個 hard + 0 個 soft dispute
- decide_status — 依 tier + dispute 結果決定 status
Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis
結論:Cortisol significantly reduced (MD -1.16 ug/dL, 95% CI -1.64 to -0.69, p<0.001); PSS not significantly changed (SMD -0.355, p=0.40)
前往 PubMed
The effect of Withania somnifera (Ashwagandha) on mental health symptoms in individuals with mental disorders: systematic review and meta-analysis
結論:Stress symptoms reduced significantly (SMD -0.95, 95% CI -1.46 to -0.43); also improved anxiety, depression, sleep
前往 PubMed
A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones
結論:Significant improvement in PSS and GAD-7 vs placebo; greater morning salivary cortisol reduction in ashwagandha arm
前往 PubMed
Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis
結論:HAM-A significantly reduced (MD -5.96, 95% CI -10.34 to -1.59, p=0.008, I2=98%); sleep improved on SOL/TST/PSQI/SE
前往 PubMed
L5a NIH Office of Dietary Supplements
謹慎
ashwagandha extracts may lower stress, anxiety, and cortisol levels 來源↗
L5b Mayo Clinic
謹慎
studies have also shown improvement in cortisol levels 來源↗
L5c Cleveland Clinic
中性
Less cortisol can mean you feel less stressed mentally 來源↗
L5d Harvard Health
未表態
— 本適應症無對應資料
L5e Specialty Society (condition-mapped)
未表態
— 本適應症無對應資料
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查看 ClaimReview 結構化資料 (JSON-LD)
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