黑種草籽 Black Seed × 膽固醇
The trial body is large and directionally consistent: multiple independent meta-analyses (17, 34 and 82 RCTs, pooling roughly 2,300 to 5,000 participants) all find that Nigella sativa significantly lowers total cholesterol, LDL-C and triglycerides, with reasonably tight confidence intervals and a coherent dose-response signal (~3000 mg/day for 12 weeks).
The trial body is large and directionally consistent: multiple independent meta-analyses (17, 34 and 82 RCTs, pooling roughly 2,300 to 5,000 participants) all find that Nigella sativa significantly lowers total cholesterol, LDL-C and triglycerides, with reasonably tight confidence intervals and a coherent dose-response signal (~3000 mg/day for 12 weeks). This consistency across many separate pooled analyses pushes the grade above C. However, it is held back from A by three real weaknesses: the underlying RCTs are predominantly small, short Middle-East and South-Asia studies with heterogeneous preparations (seed, powder, oil) and undisclosed funding; a 2023 umbrella review found that of 110 outcome indicators only 5 were moderate-quality and 88 were very-low GRADE certainty; and HDL-C effects remain inconsistent across analyses. A defensible final grade is B for surrogate lipid markers, matching Examine's General-Cardiovascular-Health B rating, with the honest caveat that GRADE certainty for any single estimate is low.
評分透明度
所有分數由 7 層證據引擎計算，過程公開可查▸查看完整決策路徑（audit trail）
- compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.525
- tier_from_score — 依分數區間映射至 tier letter
- apply_hec_rules — 高品質 SR/MA 顯示 positive (4 篇 > 0 negative)
- tier_strict_requirement_check — Tier 條件達標，未降階
- detect_disputes — 偵測到 0 個 hard + 0 個 soft dispute
- decide_status — 依 tier + dispute 結果決定 status
台灣社群（PTT/Dcard/Mobile01）幾乎查無「黑種草籽用於降膽固醇」的原生討論。膽固醇相關討論集中在紅麴、魚油、納豆激酶等熱門品項；黑種草此題幾乎被保健品牌官網、代工廠行銷文、痞客邦與假『PTT/Dcard推薦排行榜』業配文霸佔，社群真實訊號極弱。
無共識（針對膽固醇無可辨識的鄉民實測心得）
- 心臟健康飲食型態
- 生活型態調整（規律運動、健康體重、戒菸）
- 史他汀類降血脂藥物
查看 ClaimReview 結構化資料 (JSON-LD)
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