Legacy AI grade · Sources dated 2026-06-08. Not expert reviewed. Coverage is limited to the listed sources. About the new summary workflow

Psyllium Fiber for Weight Loss

Verdict: Counter-Evidence

Across 4 PubMed studies, the evidence for Psyllium Fiber in Weight Loss grades Tier D — counter-evidence. High-quality evidence indicates it is not effective (or is harmful) for this use.

D 🔴 D Counter-Evidence Counter-Evidence

🔬Why this grade7-layer evidence engine

⚖️

Scoring transparency

All scores computed by a 7-layer evidence engine — fully auditable
Raw score 0.44
D
C
B
A
S
← counter-evidence / ineffectiveeffective / strong evidence →
Final grade
D · Counter-Evidence
Confidence
81%
Highly consistent evidence
Evidence level
E2
Multiple high-quality MAs (≥2 independent, consistent)

How strongly each layer supports this effect

lower = less supportive
L11 AI re-checkIndependent read
0.30
L2 PubMedPrimary literature
0.45
L3 MechanismPlausibility
0.45
L1 ExamineGlobal benchmark
0.50
L5 Clinical bodiesAuthoritative stance
0.55
Against Mixed Supports
▸View the full decision path (audit trail)
  1. compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.442
  2. tier_from_score — 依分數區間映射至 tier letter
  3. apply_hec_rules — 高品質 SR/MA 顯示 positive (2 篇 > 1 negative)
  4. tier_strict_requirement_check — Tier 條件達標,未降階
  5. detect_disputes — 偵測到 0 個 hard + 1 個 soft dispute
  6. decide_status — 依 tier + dispute 結果決定 status

📄PubMed studies (4)L2 · primary research & systematic reviews

The effects of psyllium supplementation on body weight, body mass index and waist circumference in adults: A systematic review and dose-response meta-analysis of randomized controlled trials
PMID: 30880409 2019 統合分析
Finding: Across 22 RCTs psyllium supplementation showed no significant effect on body weight (MD -0.28 kg, 95% CI -0.78 to 0.21, p=0.268), BMI (MD -0.19 kg/m2, 95% CI -0.55 to 0.15, p=0.27) or waist circumference (MD -1.2 cm, 95% CI -2.6 to 0.2, p=0.09).
Effect size: MD body weight -0.28 kg (NS); BMI -0.19 kg/m2 (NS); WC -1.2 cm (NS)
View on PubMed
Psyllium is a natural nonfermented gel-forming fiber that is effective for weight loss: A comprehensive review and meta-analysis
PMID: 37163454 2023 統合分析 n = 354
Finding: In 6 RCTs of overweight and obese adults psyllium dosed before meals reduced body weight (MD -2.1 kg, 95% CI -2.6 to -1.6, p<0.001), BMI (MD -0.8 kg/m2, 95% CI -1.0 to -0.6, p<0.001) and waist circumference (MD -2.2 cm, 95% CI -2.9 to -1.4, p<0.001).
🟠 Limited quality ⚠️ Industry-funded Effect size: MD body weight -2.1 kg; BMI -0.8 kg/m2; WC -2.2 cm
View on PubMed
The effect of psyllium consumption on anthropometric indices: a systematic review and dose-response meta-analysis of randomized controlled trials
PMID: 41126340 2025 統合分析 n = 1,352
Finding: Across 27 RCTs psyllium significantly increased body weight (WMD +3.57, 95% CI 1.43 to 5.72, p<0.05) with non-significant changes in BMI (WMD -0.06, 95% CI -0.68 to 0.55, p>0.05), WHR (WMD -0.10, 95% CI -0.34 to 0.12, p>0.05) and WC (WMD +0.72, 95% CI -0.93 to 2.37, p>0.05); authors attribute the weight increase partly to water retention from psyllium gel.
Government Effect size: WMD body weight +3.57 (significant increase); BMI -0.06 (NS); WC +0.72 (NS)
View on PubMed
Satiety effects of psyllium in healthy volunteers
PMID: 27166077 2016 隨機對照試驗
Finding: All psyllium doses produced directional or significant reductions in inter-meal hunger versus placebo; 6.8 g significantly reduced 3-day mean hunger and desire to eat and increased fullness (p<=0.004). Outcome was appetite/satiety, not body weight.
⚠️ Industry-funded Effect size: Significant reduction in hunger and desire to eat; increased fullness at 6.8 g
View on PubMed

🏛️Regulatory & authoritative positionsL4/L5 · FDA / EMA / NIH ODS / Cochrane / Mayo …

L4a US FDA
Supportive
Diets low in saturated fat and cholesterol that include [soluble fiber amount] of soluble fiber per day from [psyllium source name] may reduce the risk of heart disease. One serving of [food name] provides ___ grams of this soluble fiber. source↗
L4b EU EFSA
Supportive
L4c UK NHS
Supportive
Ispaghula husk is a laxative taken to treat constipation (difficulty pooing). It works by bulking poo up with fluid so that it's softer. It usually takes 2 or 3 days to work. source↗
L4d TW TFDA / 衛福部
Neutral
洋車前子(殼),列載於「可供食品使用原料彙整一覽表」草、木本植物類;應於產品標示警語「請與足量的水一起食用,對洋車前子過敏者不宜食用」。 source↗
L4e WHO
Supportive
Semen Plantaginis. WHO Monographs on Selected Medicinal Plants, Volume 1 (WHO, Geneva, 1999): the crude drug consists of the dried ripe seeds of Plantago ovata Forssk. (Plantago ispaghula Roxb.); therapeutic uses supported by clinical data include occasional constipation, conditions in which easy defecation with soft stools is desirable (anal fissures, haemorrhoids, after anorectal surgery), an… source↗
L5a NIH Office of Dietary Supplements
Cautious
L5c Cleveland Clinic
Neutral
L5e Specialty Society (condition-mapped)
Not addressed
✓PMID 100% verifiedevery citation checked via NCBI Entrez
🔬4 PubMed studiesindependently re-checked by multiple sub-agents
engine_version: v1.0 claim_id: CLM-COND-weight-loss-INT-psyllium-fiber-001 繁體中文版 →