Molybdenum for Micronutrient Deficiency
Verdict: Insufficient Evidence
Across 2 PubMed studies, the evidence for Molybdenum in Micronutrient Deficiency grades Tier U — unverified / insufficient. Research is still too limited to draw a firm conclusion.
U ⚫ U Unverified Insufficient Evidence
Why this grade7-layer evidence engine
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Scoring transparency
All scores computed by a 7-layer evidence engine — fully auditableRaw score 0.52
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C
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Final grade
U · Insufficient Evidence
Confidence
78%
Broadly consistent
Evidence level
E3
Single high-quality meta-analysis
▸View the full decision path (audit trail)
- compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.515
- tier_from_score — 依分數區間映射至 tier letter
- apply_hec_rules — 無高階證據可裁決
- tier_strict_requirement_check — Tier 條件達標，未降階
- detect_disputes — 偵測到 0 個 hard + 0 個 soft dispute
- decide_status — 依 tier + dispute 結果決定 status
PubMed studies (2)L2 · primary research & systematic reviews
Amino acid intolerance during prolonged total parenteral nutrition reversed by molybdate therapy
Finding: The only documented human case of acquired dietary/nutritional molybdenum deficiency; symptoms in a long-term TPN patient resolved on molybdate supplementation; uncontrolled n=1, no statistics.
View on PubMed Molybdenum - a scoping review for Nordic Nutrition Recommendations 2023
Finding: Dietary Mo deficiency does not occur in healthy people on a normal diet; intakes routinely exceed requirements, so there is no deficiency to correct via oral supplementation.
View on PubMed Regulatory & authoritative positionsL4/L5 · FDA / EMA / NIH ODS / Cochrane / Mayo …
L4a US FDA
Supportive
The DV for molybdenum is 45 mcg for adults and children age 4 years and older. source↗
L4b EU EFSA
Supportive
Molybdenum contributes to normal sulphur amino acid metabolism. source↗
L4c UK NHS
Cautious
Molybdenum is found in many different types of food, such as nuts, canned vegetables, peas, leafy vegetables (like broccoli and spinach), cauliflower and cereals. You should be able to get all the molybdenum you need from your daily diet. source↗
L4d TW TFDA / 衛福部
Neutral
鉬 (Molybdenum) 列於「食品添加物使用範圍及限量暨規格標準」第(七)類營養添加劑，得使用之化合物包括鉬酸鈉 (Sodium molybdate)、鉬酸銨 (Ammonium molybdate)，限用於補充膳食營養之食品 (如錠狀、膠囊狀食品及綜合維生素礦物質產品)，並依使用限量及對象規定添加。 source↗
L4e WHO
Not addressed
Molybdenum is considered to be an essential trace element in both animals and humans. Safe and adequate intake levels have been suggested... namely 0.015-0.04 mg/day for infants, 0.025-0.15 mg/day for children aged 1-10 and 0.075-0.25 mg/day for all individuals above the age of 10. The guideline value of 0.07 mg/litre is consistent with the essential daily requirement for molybdenum. source↗
L5a NIH Office of Dietary Supplements
Supportive
Molybdenum deficiency has not been reported, except in people with a genetic mutation that prevents the synthesis of molybdopterin and therefore of sulfite oxidase. In this rare metabolic disorder, known as molybdenum cofactor deficiency, mutations in one of several genes prevent the biosynthesis of molybdopterin. … Molybdenum is not a standard treatment for any disease or disorder. source↗
L5d Harvard Health
Supportive
Molybdenum is a trace mineral... A deficiency of molybdenum is rare in healthy people because the amount needed in the diet is very low and it is found in a wide variety of foods. People at greatest risk are those fed intravenously (parenteral nutrition) for long periods of time. source↗