Valerian for Insomnia

Verdict: Weak evidence: helps how sleep feels, not measured sleep

Valerian earns only a weak (Tier C) rating for insomnia: pooled trials suggest it may modestly improve how rested people feel, but it does not measurably shorten the time to fall asleep or extend sleep duration. Major sleep specialists actively recommend against relying on it.

C 🟠 C Weak Evidence Taiwan Regulatory Restriction

🔬Why this grade7-layer evidence engine

The grade rests on three meta-analyses that all point the same, limited direction. Bent 2006 (PMID 17145239, n=1093) found roughly 1.8 times higher odds of self-reported sleep improvement, and Fernandez-San-Martin 2010 (PMID 20347389) echoed a modest subjective benefit (RR 1.37). But the same Fernandez analysis showed essentially no objective effect, with sleep latency improving by just 0.70 minutes. Shinjyo 2020 (PMID 33086877, n=1065) again found only subjective gains.

Several quality problems hold the score at weak rather than moderate. Trials varied widely in dose, valerian preparation, and duration; most carried significant methodological limitations; and Bent 2006 flagged possible publication bias. In short, the strongest, most measurable outcomes (time to fall asleep, total sleep) show no clear effect, while the positives are softer self-reported impressions.

Authorities are split, which is why this claim is treated as disputed. The WHO monograph supports valerian as a mild sedative, and the Mayo Clinic notes it may modestly improve sleep quality (though not duration or severity, and only after weeks). The FDA recognizes it only as a flavoring, not a sleep treatment, and the American Academy of Sleep Medicine explicitly suggests clinicians not use valerian for insomnia. It is also flagged for interactions with sedatives and alcohol, so caution is warranted.

⚖️

Scoring transparency

All scores computed by a 7-layer evidence engine — fully auditable
Raw score 0.54
D
C
B
A
S
← counter-evidence / ineffectiveeffective / strong evidence →
Final grade
C · Taiwan Regulatory Restriction
Confidence
80%
Highly consistent evidence
Evidence level
E2
Multiple high-quality MAs (≥2 independent, consistent)

How strongly each layer supports this effect

lower = less supportive
L5 Clinical bodiesAuthoritative stance
0.39
L1 ExamineGlobal benchmark
0.50
L11 AI re-checkIndependent read
0.50
L2 PubMedPrimary literature
0.60
L3 MechanismPlausibility
0.65
Against Mixed Supports
View the full decision path (audit trail)
  1. compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.539
  2. tier_from_score — 依分數區間映射至 tier letter
  3. apply_hec_rules — 高品質 SR/MA 顯示 positive (3 篇 > 0 negative)
  4. tier_strict_requirement_check — Tier 條件達標,未降階
  5. detect_disputes — 偵測到 1 個 hard + 0 個 soft dispute
  6. decide_status — 依 tier + dispute 結果決定 status

📄PubMed studies (3)L2 · primary research & systematic reviews

Valerian for sleep: a systematic review and meta-analysis (Bent et al.)
PMID: 17145239 2006 統合分析 n = 1,093
Finding: 6 of 16 trials reporting dichotomous sleep quality showed statistically significant benefit; RR of improved sleep = 1.8.
Government Effect size: RR 1.8 (95% CI 1.2-2.9)
View on PubMed
Effectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trials (Fernandez-San-Martin et al.)
PMID: 20347389 2010 統合分析
Finding: Dichotomous subjective improvement favored valerian (RR 1.37); but sleep latency MD 0.70 min and VAS SMD -0.02 showed no quantitative/objective effect.
Effect size: RR 1.37 (95% CI 1.05-1.78); sleep latency MD 0.70 min (95% CI -3.44 to 4.83); VAS SMD -0.02 (95% CI -0.35 to 0.31)
View on PubMed
Valerian Root in Treating Sleep Problems and Associated Disorders - A Systematic Review and Meta-Analysis (Shinjyo et al.)
PMID: 33086877 2020 系統性回顧 n = 1,065
Finding: 10 trials (n=1065) showed subjective sleep-quality benefit; effects more reliable for whole root/rhizome and herbal combinations; no severe adverse events.
Academic
View on PubMed

🏛️Regulatory & authoritative positionsL4/L5 · FDA / EMA / NIH ODS / Cochrane / Mayo …

L4a US FDA
Neutral
Valerian Root Oil (Valeriana officinalis L.): 21 CFR 172.510; Used for: FLAVORING AGENT OR ADJUVANT; FEMA GRAS Publication No(s).: 3; FEMA No. 3100; CAS Reg. No. 8008-88-6. source↗
L4e WHO
Supportive
Medicinal uses. Uses supported by clinical data: As a mild sedative and sleep-promoting agent. The drug is often used as a milder alternative or a possible substitute for stronger synthetic sedatives, such as the benzodiazepines, in the treatment of states of nervous excitation and anxiety-induced sleep disturbances. Contraindications: Radix Valerianae should not be used during pregnancy or lac… source↗
L5b Mayo Clinic
Cautious
Valerian root is an herbal remedy which has shown to modestly improve sleep quality in various studies but may take several weeks to see benefit. However, the herbal remedy does not seem to improve sleep duration or insomnia severity. source↗
L5c Cleveland Clinic
Neutral
VALERIAN (vuh LEER ee uhn) may support relaxation and sleep. source↗
L5e Specialty Society (condition-mapped)
Against
We suggest that clinicians not use valerian as a treatment for sleep onset or sleep maintenance insomnia (versus no treatment) in adults source↗
PMID 100% verifiedevery citation checked via NCBI Entrez
🔬3 PubMed studiesindependently re-checked by multiple sub-agents
engine_version: v1.0 claim_id: CLM-COND-insomnia-INT-valerian-001 繁體中文版 →