Bacopa Monnieri for ADHD
Bacopa monnieri has only weak and conflicting evidence for childhood ADHD: a handful of small trials hint at modest benefit, but the best-designed study missed its main behavioral outcome, and specialty bodies say there is not enough evidence that it reduces ADHD symptoms.
Why this grade7-layer evidence engine
The grade rests on a thin, mostly small-trial base. The strongest study, a 2022 double-blind RCT in 93 boys aged 6 to 14 (PMID 35041248), found no significant difference on its primary behavioral outcome; benefits appeared only on secondary cognitive, executive-function and sleep measures, and the trial was funded by a supplement manufacturer. A 2016 systematic review (PMID 27912958) pooled five pediatric studies and reported a small-to-medium effect (mean d=0.42) on hyperactivity and attention, but its authors explicitly called for more rigorous replication.
The remaining support is weaker still. A 2014 open-label study (PMID 24682000) reported broad symptom improvement but had no control group and only 31 children. A 2022 systematic review and meta-analysis of herbal ADHD treatments (PMID 35592415) listed bacopa among herbs with a 'fair indication' of efficacy and safety, yet concluded there was inadequate proof to strongly recommend herbal therapy for ADHD.
Expert guidance reinforces the cautious verdict. CHADD names bacopa among complementary products and states plainly that 'there is not enough evidence that these herbs and supplements decrease ADHD symptoms.' US regulators treat it only as a dietary supplement, and major clinical references (Mayo Clinic, Cleveland Clinic, Harvard Health, NIH ODS, NHS, EFSA, WHO) offer no specific endorsement for ADHD. Together this yields genuinely mixed, weak evidence rather than a clear positive signal.
Scoring transparency
All scores computed by a 7-layer evidence engine — fully auditable▸View the full decision path (audit trail)
- compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.537
- tier_from_score — 依分數區間映射至 tier letter
- apply_hec_rules — 無高階證據可裁決
- tier_strict_requirement_check — Tier 條件達標，未降階
- detect_disputes — 偵測到 1 個 hard + 0 個 soft dispute
- decide_status — 依 tier + dispute 結果決定 status