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Pea Protein for Weight Loss

Verdict: Published with Warning

Across 5 PubMed studies, the evidence for Pea Protein in Weight Loss grades Tier C — weak evidence. Effective, but with safety or population caveats.

C 🟠 C Weak Evidence Published with Warning

🔬Why this grade7-layer evidence engine

⚖️

Scoring transparency

All scores computed by a 7-layer evidence engine — fully auditable
Raw score 0.66
D
C
B
A
S
← counter-evidence / ineffectiveeffective / strong evidence →
Final grade
C · Published with Warning
Confidence
60%
Broadly consistent
Evidence level
E3
Single high-quality meta-analysis

How strongly each layer supports this effect

lower = less supportive
L1 ExamineGlobal benchmark
0.50
L11 AI re-checkIndependent read
0.50
L3 MechanismPlausibility
0.65
L5 Clinical bodiesAuthoritative stance
0.70
L2 PubMedPrimary literature
0.75
Against Mixed Supports
▸View the full decision path (audit trail)
  1. compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.663
  2. tier_from_score — 依分數區間映射至 tier letter
  3. apply_hec_rules — 高品質 SR/MA 顯示 positive (1 篇 > 0 negative)
  4. tier_strict_requirement_check — Tier 條件達標，未降階
  5. detect_disputes — 偵測到 0 個 hard + 0 個 soft dispute
  6. decide_status — 依 tier + dispute 結果決定 status

📄PubMed studies (5)L2 · primary research & systematic reviews

Effect of different protein sources on satiation and short-term satiety when consumed as a starter
PMID: 22196620 2011 RCT (open-label) n = 32
Finding: Food intake was significantly lower only after casein and pea protein vs. water control (p=0.02 and p=0.04 respectively); whey did not reach significance.
🟠 Limited quality ⚠️ Industry-funded Effect size: null (energy intake difference not reported in kcal with CI)
View on PubMed
Intraduodenal administration of intact pea protein effectively reduces food intake in both lean and obese male subjects
PMID: 21931864 2011 RCT (open-label) n = 20
Finding: Intraduodenal pea protein reduced food intake by 168.9±40 kcal (lean, p<0.01) and 298.2±44 kcal (obese, p<0.01); oral route showed smaller non-significant effects.
🟠 Limited quality Effect size: MD -168.9 kcal (lean); MD -298.2 kcal (obese)
View on PubMed
Protein Source Influences Acute Appetite and Satiety but Not Subsequent Food Intake in Healthy Adults
PMID: 37030593 2023 RCT (open-label) n = 32
Finding: Casein and pea protein significantly reduced 4-h appetite vs. soy (p<0.05) and increased peptide YY (p<0.05); no differences in ad libitum energy intake across sources.
Effect size: null (no significant energy intake difference)
View on PubMed
The Short-Term Effect of Whey Compared with Pea Protein on Appetite, Food Intake, and Energy Expenditure in Young and Older Men
PMID: 32072131 2020 RCT (open-label) n = 30
Finding: No significant effect of protein source (pea vs. whey) on appetite markers, food intake, or energy expenditure; age significantly modulated energy expenditure.
🟠 Limited quality Effect size: null (no significant difference between sources)
View on PubMed
Are Dietary Proteins the Key to Successful Body Weight Management? A Systematic Review and Meta-Analysis of Studies Assessing Body Weight Outcomes
PMID: 34579069 2021 統合分析 n = 43
Finding: High-protein diets reduced body weight by ~1.6 kg more than controls (95% CI 1.2–2.0 kg); no pea-protein-specific subgroup analyzed.
Effect size: MD -1.6 kg (95% CI -2.0 to -1.2 kg)
View on PubMed

🏛️Regulatory & authoritative positionsL4/L5 · FDA / EMA / NIH ODS / Cochrane / Mayo …

L4a US FDA
Supportive
FDA has no questions regarding the GRAS status of this substance, based on scientific procedures provided by the notifier. source↗
L4b EU EFSA
Supportive
L4d TW TFDA / 衛福部
Neutral
豌豆仁（豌豆）已收錄於食藥署「食品營養成份資料庫」（consumer.fda.gov.tw），為蔬菜類一般食品。豌豆蛋白（分離豌豆蛋白、豌豆蛋白粉）以一般食品身分在台灣市場流通，未取得健康食品許可證（小綠人）。依《包裝食品營養宣稱應遵行事項》（113年2月19日修正），固態食品每100公克蛋白質含量達12公克以上，始得宣稱「高蛋白質」。 source↗
L5c Cleveland Clinic
Supportive
L5d Harvard Health
Neutral
✓PMID 100% verifiedevery citation checked via NCBI Entrez
🔬5 PubMed studiesindependently re-checked by multiple sub-agents
engine_version: v1.0 claim_id: CLM-COND-weight-loss-INT-pea-protein-001 繁體中文版 →