Boron for Testosterone
Boron is not an established testosterone booster. The only direct evidence in men is a tiny, uncontrolled 7-day trial, and major regulators and urology societies do not endorse it for raising testosterone.
Why this grade7-layer evidence engine
The grade is weak because the human evidence is thin and mostly indirect. The single study in men, Naghii 2011 (PMID 21129941), gave 10 mg/day of boron to just 8 healthy men for 7 days and saw free testosterone rise about 28%. But it had no placebo group, an extremely small sample, and tracked only short-term blood markers, so it is hypothesis-generating rather than proof of a real-world benefit.
The rest of the literature does not strengthen the case. The data cited most in marketing, Nielsen 1987 (PMID 3678698), tested postmenopausal women being repleted from a boron-deficient diet, which does not transfer to men with normal hormone levels. A placebo-controlled trial in young women (PMID 7840072) found no effect on testosterone, and Pizzorno's 2015 review (PMID 26770156) is a narrative summary, not a systematic analysis, that merely restates these small studies.
Authorities reflect this uncertainty. EFSA concluded a cause-and-effect link between boron intake and normal plasma testosterone has not been established, and Mayo Clinic says boron supplementation cannot be recommended on current research, cautioning it may act like estrogen. The AUA and Endocrine Society testosterone guidelines do not mention it. Typical doses appear generally safe (EFSA upper limit 10 mg/day), but boron should be treated as unproven, not a therapy.
Scoring transparency
All scores computed by a 7-layer evidence engine — fully auditable▸View the full decision path (audit trail)
- compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.4
- tier_from_score — 依分數區間映射至 tier letter
- apply_hec_rules — 無高階證據可裁決
- tier_strict_requirement_check — Tier 條件達標，未降階
- detect_disputes — 偵測到 0 個 hard + 0 個 soft dispute
- decide_status — 依 tier + dispute 結果決定 status