Astragalus for Common Cold

Verdict: Weak evidence; no proof astragalus alone helps

There is no reliable evidence that astragalus on its own prevents or treats the common cold. The few positive signals come from multi-herb formulas or a special patient group, not from astragalus taken by itself.

C 🟠 C Weak Evidence Published

🔬Why this grade7-layer evidence engine

This claim earns a Weak (C) grade mainly because the highest-quality evidence is a blank. A 2016 Cochrane systematic review (PMID 27905672) screened 6,080 records and could not find a single randomized trial of oral astragalus used on its own for respiratory infection, so its real-world effectiveness and safety in healthy people remain untested.

The apparent positives are easy to misread. A 2016 meta-analysis (PMID 27145435) of the Yupingfeng formula reported a higher clinical response rate (RR 1.21), but astragalus is just one of three herbs, so the benefit cannot be pinned on astragalus itself. A small 2013 review (PMID 23662131) found fewer infections (RR 0.56) only in children with nephrotic syndrome, a special group that does not generalize to ordinary colds. Both were rated low quality.

Authorities offer no support. The US FDA lists only tragacanth gum as a food additive, not astragalus as a cold remedy, and major clinics (Mayo, Cleveland Clinic, Harvard, NIH ODS) do not address it. Astragalus may also interact with immunosuppressant drugs, so people who are immune-compromised or on such medication should be cautious.

⚖️

Scoring transparency

All scores computed by a 7-layer evidence engine — fully auditable
Raw score 0.58
D
C
B
A
S
← counter-evidence / ineffectiveeffective / strong evidence →
Final grade
C · Published
Confidence
79%
Broadly consistent
Evidence level
E2
Multiple high-quality MAs (≥2 independent, consistent)

How strongly each layer supports this effect

lower = less supportive
L1 ExamineGlobal benchmark
0.50
L11 AI re-checkIndependent read
0.50
L5 Clinical bodiesAuthoritative stance
0.55
L2 PubMedPrimary literature
0.60
L3 MechanismPlausibility
0.65
Against Mixed Supports
View the full decision path (audit trail)
  1. compute_raw_score — 加權公式: L2×0.30 + L3×0.25 + L5×0.25 + L11×0.10 + L1×0.10 = 0.58
  2. tier_from_score — 依分數區間映射至 tier letter
  3. apply_hec_rules — 高品質 SR/MA 顯示 positive (1 篇 > 0 negative)
  4. tier_strict_requirement_check — | B→C 因 scope.conflation_risk=true 且 L11 獨評較低 (B7-2 tier cap)
  5. detect_disputes — 偵測到 0 個 hard + 0 個 soft dispute
  6. decide_status — 依 tier + dispute 結果決定 status

📄PubMed studies (3)L2 · primary research & systematic reviews

Oral Astragalus (Huang qi) for preventing frequent episodes of acute respiratory tract infection in children
PMID: 27905672 2016 系統性回顧 n = 0
Finding: Cochrane review screened 6080 records; no RCTs of oral Astragalus as a sole intervention met inclusion criteria, so effectiveness and safety could not be assessed.
🟢 High quality Government
View on PubMed
Astragalus in the prevention of upper respiratory tract infection in children with nephrotic syndrome: evidence-based clinical practice
PMID: 23662131 2013 系統性回顧 n = 2
Finding: Astragalus granules reduced URTI incidence vs prednisone alone (23.9% vs 42.9%; RR=0.56, 95% CI 0.33-0.93).
🟠 Limited quality Effect size: RR 0.56 (95% CI 0.33-0.93)
View on PubMed
Adjuvant Treatment with Yupingfeng Formula for Recurrent Respiratory Tract Infections in Children: A Meta-analysis of RCTs
PMID: 27145435 2016 統合分析 n = 1,236
Finding: Adjuvant Yupingfeng raised clinical effective rate (RR=1.21, 95% CI 1.13-1.29) and immunoglobulins (IgG WMD=2.89), but effect attributed to multi-herb formula, not astragalus alone.
🟠 Limited quality Effect size: RR 1.21 (95% CI 1.13-1.29)
View on PubMed

🏛️Regulatory & authoritative positionsL4/L5 · FDA / EMA / NIH ODS / Cochrane / Mayo …

L4a US FDA
Cautious
TRAGACANTH, GUM (ASTRAGALUS SPP.) source↗
L4d TW TFDA / 衛福部
Neutral
215種『可同時提供食品使用之中藥材』 source↗
PMID 100% verifiedevery citation checked via NCBI Entrez
🔬3 PubMed studiesindependently re-checked by multiple sub-agents
engine_version: v1.0 claim_id: CLM-COND-common-cold-INT-astragalus-001 繁體中文版 →